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FamLinkX
is compatible with all Windows version from XP and the installation files are
provided in link below.
When downloading FamLinkX, you are encouraged to send us an email including:
- your name
- the name and location of your institution
- any comments you might have about the program
With this information, we can keep track of how FamLinkX is used, and we can
notify you about possible updates of the program.
Validation files may be found here
(Excel file with pedigree names and values to fill in as well as FamLinkX save
files)
Population
|
Size
|
Database
|
Publication
|
Comment
|
Sweden
|
652
|
SWE
|
Tillmar
A.
|
|
Norway
|
631
|
NOR
|
Bergseth et al.
|
|
Czech Repubic
|
307
|
CZE
|
Zidkova
et al.
|
|
Germany
|
1037
|
GER
|
Edelmann
et al.
|
|
Greece
|
121
|
GRE
|
Tomas
et al.
|
|
Italian
|
200
|
ITA
|
Bini
et al.
|
|
Sardinia
|
316
|
SAR
|
Robino
et al.
|
|
Serbia
|
220
|
SER
|
Veselinovic
et al.
|
|
Hungary
|
219
|
HUN
|
Horvath
et al.
|
|
Portugal
|
150
|
POR
|
Caine
et al.
|
|
United Arab Emirates
|
501
|
UAE
|
Almarri
et al.
|
|
Somali
|
673
|
SOM
|
Kling
et al.
|
|
Egypt
|
257
|
EGY
|
Elakkary
et al.
|
|
India
|
100
|
IND
|
Shrivastava
et al.
|
|
Bangladesh
|
102
|
BAN
|
Sufian et
al.
|
|
Philippines
|
143
|
PHI
|
Salvador
et al.
|
|
China
|
263
|
CHI
|
Guo
F.
|
|
China (Korea)
|
257
|
KOR
|
Xiao-na
et al.
|
No micro-variants present
|
Japan
|
438
|
JAP
|
Uchigasaki
et al.
|
|
Thailand
|
282
|
THA
|
Vongpaisarnsin
et al.
|
|
Mexico
|
933
|
MEX
|
Cortés-Trujillo
et al.
|
|
Argentina
|
912
|
ARG
|
Garcia
et al.
|
|
Northern Europe
|
2624
|
NEU
|
-
|
SWE,
NOR, GER, CZE
|
Eastern Asia
|
1126
|
EAS
|
-
|
PHI,
CHI, JAP, THA
|
Southern Europe
|
1009
|
SEU
|
-
|
POR,
SER, SAR, ITA GRE
|
FamLinkX v.2.9.3
(Released TBA)
- Added several pedigrees.
Use new pedigrees with caution
- Corrected a few minor bugs
- Improved simulation
feature
FamLinkX v.2.9.2
(Released 2020-06-03)
- Fixed some bugs related to
the import of genotype data
FamLinkX v.2.9.1
(Released 2020-05-25)
- Fixed some minor bugs
FamLinkX v.2.9 (Released
2019)
- Import of data on
Genemapper format is now possible.
- Fixed crash when
generating report using created pedigrees.
- Added a few new pedigrees.
Please check those carefully before using.
FamLinkX v.2.8 (Released
2019-01-01)
- Fixed bugs and made
smaller updates.
- Implemented a new
frequency model based on pseudo counts. Briefly the model can be described as
an extension of the lambda-model whereby pseudo counts (i.e. haplotypes
observed in a case) is added. If activated this will make the frequency
estimation model less sensitive to the choice of lambda.
- Plotting of pedigrees.
Yes, we are excited to introduce the ability to plot pedigrees (created) in R
and import back into FamLinkX.
FamLinkX v.2.7 (Early
release 2018-08-30)
- Fixed minor bugs.
FamLinkX v.2.6 (Released
2017-01-18)
- Fixed minor bugs.
- Included some new
pedigrees.
- Self validation feature
available via Tools menu. This function will create a series of tests to find
all pedigrees.
- Made updates to the
report. Now includes marker likelihoods, references and some additional text.
- Simulation module has been
thoroughly tested and updated. Should now work and produce correct results for
all predefined pedigrees. Please report any bugs you encounter.
- Export/import
functionality in connection with cluster and markers has been revised. Users of
Decaplex (or similar single marker clusters) can now enjoy simple import of
allele frequencies.
- Automatic sorting of
clusters and markers before computations.
FamLinkX v.2.5 (Released
2016-08-22)
- Fixed several bugs in the
create pedigree feature.
FamLinkX v.2.4.1
(Released 2016-06-05)
- Fixed bug that was caused
by the introduction of cluster specific lambdas causing FamLinkX not to update
the calculations when new lambdas were chosen.
FamLinkX v.2.4 (Released
2016-05-29)
- Fixed smaller bugs
- Updated report to include
also individual marker LRs
FamLinkX v.2.3 (Released
2016-02-15)
- Minor bugs fixed.
- It is now possible to
import xml files on the CODIS format
- Fixed issue that caused an
extra empty pedigree to appear when creating your own pedigrees
- Fixed crash when using
kits with single marker clusters (e.g. Decaplex)
FamLinkX v.2.2 (Released
2015-11-07)
- Minor bugs fixed.
- Some stability issues.
- Maternal uncle (with male
as the 2nd persons) provided wrong results. Corrected
- View the data for all
persons together in the Add data
dialog.
- Specify a name for the
database, e.g. "Norwegian".
- Specify that you wish to
perform calculations using a zero mutation model (without having to change the
rate for each system). Specified in the Options
dialog.
- Made several updates to
the report. Now timestamp, file location and database name is reflected. In
addition, the gender for the persons is included.
- View the accumulated LR as
well as the marginal LR for the results. These two measures give an idea of the
contribution for each marker and cluster to the overall LR.
- The manual has received a
mayor update.
- Bug fixed that would cause
wrong calculations when using several one marker cluters. (Affects users of
Decaplex and similar kits)
- Bug fixed in the frequency
estimator dialog (Found in Edit
cluster dialog)
- The dialog when specifying
DNA data has been updated. Changing the alleles now reflect immediately.
Also, it is
now possible to
double click a specific marker in the display window, instead of choosing
Cluster->Marker manually
- Skip cluster functionality
added. It is now possible to perform calculation with incomplete allele data.
Affected cluster will be skipped (for now).
- Sorting. Before calculations, all clusters and
markers are sorted.
- Bugs when creating
pedigrees fixed
- Bug in report creator
fixed
- Several minor changes
- New: View the frequency of
individual haplotypes for different values of lambda. (Found in the Edit cluster dialog)
This version
was released 2014-11-13 and obsoletes all previous versions. Several bugs has
been smashed. In addition speed-ups and other improvements have been
implemented. (An early release of 2.0, dated 2014-11-10 contained a small bug)
Please be
aware that old calculations with older versions could be wrong, unless
internally validated.
You may send
comments to help@famlink.se