The software FamLinkX
provides functions in likelihood calculation for family relationships/pedigrees
using X-chromosomal genetic marker data. FamLinkX is a free software with no strings attached. Anyone may use the
software for non-commercial purposes. The software is developed by Daniel Kling at Norwegian Institute of Public Health, Norway, Andreas Tillmar at National Board of Forensic Medicine, Sweden, Thore Egeland at Norwegian University of Life Sciences and Petter Mostad at Chalmers University, Mathematical Sciences, Sweden. See further contact details here.
Method
FamLinkX
implements a new algorithm for genetic marker data based on Markov-chains for
inheritance patterns, similar to the Lander-Green algorithm. In addition the
algorithm implements a Markov-chain for allelic dependency (linkage
disequilibrium). Moreover, the model allows for genetic inconsistencies
(mutations). The software provides an easy-to-use graphical user interface for
windows systems. Furthermore, calculations are in addition performed using
previously published methods as a comparison. (Abecasis et al., Nat. Genet., 2002).
Using FamLinkX
Download the software and use the getting
started example and
the manual to start using FamLinkX. If
you need help in any way, please contact us. Databases for
published populations is found in the Databases page.
Validation
Files for validation of new versions may be found at
the Download section. FamLinkX implements a self validation
feature to verify some of the calculations.
Citing FamLinkX
Last updated
October, 2018
You may send comments to help@famlink.se