The
software FamLinkX provides functions in likelihood calculation for family
relationships/pedigrees using X-chromosomal genetic marker data. FamLinkX is a
free software with no strings attached. Anyone may use the software for
non-commercial purposes. The software is developed by Daniel Kling
at Norwegian Institute of Public Health, Norway, Andreas Tillmar
at National Board of Forensic Medicine, Sweden, Thore Egeland at Norwegian University
of Life Sciences and Petter Mostad at Chalmers University,
Mathematical Sciences, Sweden. See further contact details here.
Method
FamLinkX implements a new algorithm for genetic
marker data based on Markov-chains for inheritance patterns, similar to the
Lander-Green algorithm. In addition the algorithm implements a Markov-chain for
allelic dependency (linkage disequilibrium). Moreover, the model allows for
genetic inconsistencies (mutations). The software provides an easy-to-use
graphical user interface for windows systems. Furthermore, calculations are in
addition performed using previously published methods as a comparison. (Abecasis
et al., Nat. Genet., 2002).
Using FamLinkX
Download
the software and use the getting started example and the manual to start
using FamLinkX. If you need help in any way, please contact
us. Databases for published population will be available at the Download page.
Validation
Files
for validation of new versions may be found at the Download section.
FamLinkX implements a self validation feature to verify some of the
calculations.
Citing FamLinkX
Last updated October, 2018
You may send comments to help@famlink.se